Insights into age-related locomotor declines from studies of insects.
نویسندگان
چکیده
Locomotor deficits frequently accompany aging in animals. These deficits are often caused by degeneration in the nervous and musculoskeletal systems. Insects are an excellent model for age-related behavior studies because they are short-lived and have a reduced nervous system with fewer cells than vertebrates. Furthermore, they are highly mobile and display a complex set of locomotor behaviors. This review presents research that has examined age-related locomotor deficits in insects and discusses the value of these studies to understand aging processes in all animals.
منابع مشابه
Cellular immunosenescence in adult male crickets, Gryllus assimilis.
Ecological immunity studies in invertebrates, particularly insects, have generated new insights into trade-offs between immune functions and other physiological parameters. These studies document physiologically directed reallocations of immune costs to other high-cost areas of physiology. Immunosenescence, recognized as the age-related deterioration of immune functions, is another mechanism of...
متن کاملDrosophila as a model for age-related impairment in locomotor and other behaviors.
Aging is a multifaceted phenomenon that occurs in most species including humans and the fruit fly, Drosophila melanogaster. One of the most fundamental features of aging is the progressive decline in functional capacity that occurs with age (i.e. functional senescence). Age-related declines in function undermine many aspects of normal youthful physiology including behavior. Age-related behavior...
متن کاملEnabling techniques for in vitro studies on mammalian spinal locomotor mechanisms.
The neonatal rodent spinal cord maintained in vitro is a powerful model system to understand the central properties of spinal circuits generating mammalian locomotion. We describe three enabling approaches that incorporate afferent input and attached hindlimbs. (i) Sacral dorsal column stimulation recruits and strengthens ongoing locomotor-like activity, and implementation of a closed positive-...
متن کاملWhen does it all go wrong? Longitudinal studies of changes in moderate-to-vigorous-intensity physical activity across childhood and adolescence
Objective/Background There is a widespread belief that moderate-to-vigorous-intensity physical activity (MVPA) declines markedly in adolescence, particularly in girls. This belief has led to substantial research and policy effort aimed at reducing the perceived decline in MVPA during adolescence. The main aim of this review is to critically examine the belief that MVPA declines during adolescen...
متن کاملRelationships between locomotor activity, oxidative damage and life span in males and females of the linden bug, Pyrrhocoris apterus (Heteroptera: Pyrrhocoridae)
In this study we addressed a question of whether experimental manipulations that increase life span also reduce physical activity and molecular oxidative damage. We used three phenotypes of male and female Pyrrhocoris apterus that survive for different lengths of time, diapausing insects, reproductive insects and insects from which the corpus allatum, the source of juvenile hormone, was surgica...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Ageing research reviews
دوره 4 1 شماره
صفحات -
تاریخ انتشار 2005